Claire Cox
PhD Student:- Sin3A opposes c-Myc and is essential for maintenance of balanced epidermal homeostasis
Email: cc565@cam.ac.uk
Laboratory Location:
Wellcome Trust CSCR
Departmental Affiliation:
Physiology, Development and Neuroscience
My CV is attached for those that are interested.
Check out my blog at coxclaire.wordpress.com
Frye LabPlain English
The epidermis, which is the outer layer of mammalian skin, is maintained by numerous stem cell populations. The elucidation of the factors involved in controlling these populations and thus epidermal maintenance is highly valuable. Not only will it provide information as to how a complex tissue is organised and controlled, the principles that are learnt can be applied to other tissues. Through the work that I am completing, I hope that I can also gain a perspective as to what goes wrong in disease processes such as skin cancer. Skin cancer is one of the most prevalent cancers in the world, and understanding what goes wrong and the factors involved could potentially lead to new ideas as to prevention and treatment.Key Publications
View all publications by
Claire Cox
- The opposing transcriptional functions of Sin3a and c-Myc are required to maintain tissue homeostasis Nat Cell Biol. 2011 Nov 20;13(12):1395-405. doi: 10.1038/ncb2385.. Nascimento EM, Cox CL, Macarthur S, Hussain S, Trotter M, Blanco S, Suraj M, Nichols J, Kübler B, Benitah SA, Hendrich B, Odom DT, Frye M.
- Association and heterogeneity at the GAPDH locus in Alzheimer's disease. Neurobiol Aging. 2012 Jan;33(1):203.e25-33. Epub 2010 Sep 23. Allen M, Cox C, Belbin O, Ma L, Bisceglio GD, Wilcox SL, Howell CC, Hunter TA, Culley O, Walker LP, Carrasquillo MM, Dickson DW, Petersen RC, Graff-Radford NR, Younkin SG, Ertekin-Taner N.